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What is Arthrogryposis Multiplex Congenita (AMC)?

Arthrogryposis Multiplex Congenita (AMC) is a descriptive term used to describe over 300 conditions that cause multiple curved joints in areas of the body at birth.

AMC is not a specific diagnosis but rather a clinical finding of permanent shortening of joints also referred to as non-progressive congenital contractures.

In the UK alone over 260 babies are born with AMC each year, that's one in every 3,000*

Symptoms of Arthrogryposis Multiplex Congenita (AMC) vary drastically from person to person particularly as there are over 300 types of conditions that are covered by the descriptive term Arthrogryposis however the commonality being stiff joints and muscle weakness.

The areas that are most likely to have lack of movement are the shoulders, elbows, wrists, hands, hips, knees and feet. AMC is non-progressive meaning that the lack of movement, does not get worse as time goes by however, it is recommended that people affected seek advice to potentially prevent further impediments of the joints.

Occasionally AMC can also affect the central nervous system of which the survival rate can be low.

** Source: Arthrogryposis A Text Atlas Edited by Lynn T. Staheli MD, Judith G Hall MD, Kenneth M Jaffe MD

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